Surprisingly though, the hormone estrogen can play a role in the development of osteoarthritis and when a woman is under the menopausal phase. They can experience a decline in their estrogen levels, and osteoporosis will begin to wreak the bones and joints, causing chronic inflammation.
With perimenopause, it is the beginning of the menopausal transition as the female body starts to change. From hot flashes to irregular sleep patterns, perimenopause is a natural way to let the body know that change is coming.
For the blood-brain barrier, since it is an endocrine tissue, it can divide the hormone receptors.